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A published in The New England Journal of Medicine has found no correlation between COVID-19 vaccinations and risk of first-trimester miscarriages, providing further evidence of the safety of COVID-19 vaccination during pregnancy.
The study analyzed several national health registries in Norway to compare the proportion of vaccinated women who experienced a miscarriage during the first trimester and women who were still pregnant at the end of the first trimester.
鈥淥ur study found no evidence of an increased risk for early pregnancy loss after COVID-19 vaccination and adds to the findings from other reports supporting COVID-19 vaccination during pregnancy,鈥 write the study authors, which includes co-author Dr. Deshayne Fell, an Associate Professor in the School of Epidemiology and Public Health in the University of Ottawa鈥檚 Faculty of Medicine and a Scientist at the Children鈥檚 Hospital of Eastern Ontario (CHEO) Research Institute.
鈥淭he findings are reassuring for women who were vaccinated early in pregnancy and support the growing evidence that COVID-19 vaccination during pregnancy is safe.鈥
Dr. Fell, currently leading on the effectiveness and safety of COVID-19 vaccines, and the international team behind the study found no relationship between the type of vaccine received and miscarriage. In Norway, the vaccines used included Pfizer, Moderna and AstraZeneca.
鈥淚t is important that pregnant women are vaccinated since they have a higher risk of hospitalizations and COVID-19-complications, and their infants are at higher risk of being born too early. Also, vaccination during pregnancy is likely to provide protection to the newborn infant against COVID-19 infection in the first months after birth,鈥 the study authors write.
鈥Covid-19 Vaccination during Pregnancy and First-Trimester Miscarriage鈥 is published in The New England Journal of Medicine, Ocotber 20, 2021. DOI: 10.156/NEJMc2114466
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